Sirolimus + Teclistamab or Talquetamab
Impact of Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma
What's the purpose of the trial?
This is a single center, single arm Phase Ib study with expansion cohort designed to establish the safety and physiologic effects of sirolimus pre-conditioning followed by T-cell engaging bispecific antibody therapy.
Trial status
Not yet accepting
Phase
Phase 1
Enrollment
10
Last Updated
Participating Centers
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Experimental Treatments
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- Talquetamab
- Teclistamab
- Sirolimus
Arms / Cohorts
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Not yet accepting
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