Ruxolitinib Combination Therapy

Treatment of Patients with Relapsed/Refractory Multiple Myeloma with Ruxolitinib, Methylprednisolone and Lenalidomide: Using Changes in Serum B-Cell Maturation Antigen (BCMA) or International Multiple Working Group (IMWG) Criteria to Determine Disease Progression in Order to Add Lenalidomide to Those Failing the Ruxolitinib/Methylprednisolone Combination

What's the purpose of the trial?

This is a phase 1, multicenter, open-label study evaluating the safety and efficacy of ruxolitinib, steroids and lenalidomide among MM patients who currently show progressive disease using BCMA to test progression.
Trial status

Accepting patients

Phase
Phase 1
Enrollment
30
Last Updated
1 week ago
Am I Eligible

Participating Centers

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Experimental Treatments

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  • Lenalidomide
  • Methylprednisolone
  • Ruxolitinib

Arms / Cohorts

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Accepting patients

EXPERIMENTAL: Rux + Steroid

Accepting patients

EXPERIMENTAL: Rux + Steroid + Len

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