UNC Lineberger Comprehensive Cancer Center

University of North Carolina

Chapel Hill, NC

Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
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  • CAR T Cell
  • GPRC5D
  • Phase 2

Accepting patients

MonumenTAL-3

Phase 3 Clinical Trial Comparing the Efficacy of an Investigational Medication Combined with Daratumumab or Daratumumab and Pomalidomide Versus Daratumumab, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma.
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  • Bispecific Antibody
  • GPRC5D
  • Randomization
  • Phase 3
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Accepting patients

DREAMM12

A Study of Belantamab Mafodotin (GSK2857916) in Multiple Myeloma Participants With Normal and Varying Degrees of Impaired Renal Function
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  • Antibody Drug Conjugate (ADC)
  • BCMA
  • Phase 1

Accepting patients

CAR138 T-Cells

Phase I Study of Autologous CAR T-Cells Targeting the CD138 Antigen for Relapsed or Refractory Multiple Myeloma
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  • CAR T Cell
  • CD138
  • Phase 1

Accepting patients

ISB 2001

A Phase 1, First-in-Human, Multicenter, Open-Label, Dose Escalation and Dose-Expansion Study of Single-Agent ISB 2001 in Subjects With Relapsed/Refractory Multiple Myeloma
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  • T Cell
  • BCMA
  • CD38
  • Phase 1

Accepting patients

ABBV-383

A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma
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  • Bispecific Antibody
  • BCMA
  • Phase 1

Accepting patients

Registry of Older Patients With Cancer

Carolina Senior: UNC Registry for Older Cancer Patients
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  • Patient Registry
  • Observational Trial

Accepting patients

Tissue, Blood, and Body Fluid Sample Collection

Tissue Procurement For Hematolymphoid Conditions
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  • Observational Trial

Accepting patients

Isatuximab Combination Therapy

Study of Isatuximab Plus Pomalidomide and Dexamethasone in Highly Toxicity-vulnerable Subjects With Relapsed or Refractory Multiple Myeloma
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  • Immunomodulatory Drug
  • Phase 2

Not yet accepting

DISCOVERY

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics
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  • Randomization