Memorial Sloan Kettering Cancer Center

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CARTITUDE-2

Phase 2, Open-Label Study Evaluating the Use of an Investigational CAR-T Cell therapy in Participants with Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • Phase 2

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QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
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  • CAR T Cell
  • GPRC5D
  • Phase 2
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MonumenTAL-8

A Phase 2, Open-Label, Multicenter Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma
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  • Bispecific Antibody
  • CAR T Cell
  • BCMA
  • GPRC5D
  • Phase 2

Accepting patients

CA057-003

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma
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  • CELMoD
  • Phase 1/2

Accepting patients

CA088-1005

A Phase 1, Multicenter, Open-label Study to Evaluate the Safety and Preliminary Efficacy of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma and Determine the Recommended Dose for Each Add-on Investigational Component
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  • CAR T Cell
  • CELMoD
  • GPRC5D
  • Phase 1

Accepting patients

BMS-986453

A Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • GPRC5D
  • Phase 1

Accepting patients

Belantamab Mafodotin Combination Therapy

A Study of Belantamab Mafodotin in Combination With and Nirogacestat and Pomalidomide in People With Multiple Myeloma That Has Not Responded to Treatment or Has Come Back After Treatment
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  • Antibody Drug Conjugate (ADC)
  • Gamma-Secretase Inhibitor
  • BCMA
  • Phase 1

Accepting patients

Iberdomide as Maintenance Therapy

Study of Iberdomide in People With Multiple Myeloma Who Have Had an Autologous Hematopoietic Stem Cell Transplant (AHCT)
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  • CELMoD
  • Phase 2

Accepting patients

Stopping Maintenance Therapy in People With Multiple Myeloma in MRD-Negative Remission
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  • Maintenance

Accepting patients

NUTRIVENTION-4

A Study of Health-Related Quality of Life in People With Multiple Myeloma Receiving Daratumumab or Lenalidomide
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  • Monoclonal Antibody
  • CD38
  • Maintenance
  • Phase 2