UCSF Helen Diller Comprehensive Cancer Center

University of California San Francisco

San Francisco, CA

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Accepting patients

CARTITUDE-10

A Phase 2 Multicohort Trial to Further Characterize the Efficacy and Safety of Ciltacabtagene Autoleucel
  • CAR T Cell
  • BCMA
  • Phase 2

Accepting patients

Talisman

A Phase 2, Open-label, Randomized Study to Evaluate Prophylactic Interventions on Talquetamab-related Oral Toxicity
  • Bispecific Antibody
  • GPRC5D
  • Randomization
  • Phase 2

Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Phase 2

Not yet accepting

inMMyCAR

A Phase 1 Study to Evaluate the Safety of KLN-1010, a Novel, In Vivo Gene Therapy to Generate Anti-B Cell Maturation Antigen (Anti-BCMA) Chimeric Antigen Receptor-T Cells (CAR-T) in Patients With Relapsed and Refractory Multiple Myeloma
  • CAR T Cell
  • BCMA
  • Phase 1
  • Has results

Accepting patients

BMS-986453

A Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma
  • CAR T Cell
  • BCMA
  • GPRC5D
  • Phase 1

Accepting patients

MMSET Inhibitor

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
  • H3K36me2
  • Phase 1
  • Has results

Accepting patients

JNJ-79635322

Phase 1, First-in-Human, Dose Escalation Study of JNJ-79635322, a Trispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated AL Amyloidosis
  • Trispecific Antibody
  • BCMA
  • GPRC5D
  • Phase 1
  • Has results

Accepting patients

DURGA-1

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
  • CAR T Cell
  • BCMA
  • CD19
  • Phase 1/2
  • Has results

Accepting patients

CRISPR Delivered Anti-BCMA CAR-T

A Phase 1b Clinical Trial of CRISPR Delivered Anti-BCMA Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Multiple Myeloma
  • CAR T Cell
  • BCMA
  • Phase 1

Accepting patients

TRIlogy-3

A Phase 2, Open-label Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) Who Have Received at Least 3 Prior Lines of Therapy Including a PI, an IMiD, and an Anti-CD38 Antibody
  • Trispecific Antibody
  • GPRC5D
  • BCMA
  • Phase 2
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