Alvin J. Siteman Cancer Center

Washington University Medical Campus

St. Louis, MO

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Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Phase 2

Accepting patients

MonumenTAL-1

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
  • Bispecific Antibody
  • GPRC5D
  • Phase 2
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Accepting patients

Iberdomide vs. Observation Post Ide-Cel CAR-T

Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients
  • CELMoD
  • Maintenance
  • Randomization
  • Phase 2

Accepting patients

MRD-Guided Elranatamab Maintenance Therapy

Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance
  • Bispecific Antibody
  • BCMA
  • CD3
  • Maintenance
  • Phase 2

Accepting patients

Sonrotoclax (BGB-11417)

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
  • BCL-2 Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

Investigational Cord Blood Units

Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the National Cord Blood Program (NCBP) for Unrelated Transplantation
  • Allogeneic Stem Cell Transplant
  • Cord Blood
  • Phase 2

Accepting patients

Cemsidomide (CFT7455)

Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma
  • IKZF1/3
  • Phase 1/2
  • Has results

Accepting patients

AZD0305

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/​Refractory Multiple Myeloma
  • Antibody Drug Conjugate (ADC)
  • GPRC5D
  • Phase 1/2

Accepting patients

WS-CART-CS1

Phase 1 Dose-Escalation and Dose-Expansion Study of the Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma
  • Phase 1

Accepting patients

Horizon Adaptive Platform

MMRC Horizon One Adaptive Platform Trial Evaluating Therapies in RRMM
  • BCMA
  • CD3
  • Randomization
  • Phase 2
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