Medical College of Wisconsin

Froedtert Hospital

Milwaukee, WI

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Accepting patients

QUINTESSENTIAL-2

Phase 3 Clinical Trial Comparing the Safety and Efficacy of BMS-986393 to Standard of Care Regimens in Patients with Relapsed/Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Randomization
  • Phase 3

Accepting patients

MagnetisMM-30

A Phase 1B, Open-Label Study of Elranatamab in Combination with Iberdomide in Participants with Relapsed Refractory Multiple Myeloma
  • Bispecific T Cell Engager (BiTE)
  • Bispecific Antibody
  • CD3
  • BCMA
  • Phase 1
  • Has results

Accepting patients

MajesTEC-4

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation - MajesTEC-4
  • Bispecific Antibody
  • Bispecific T Cell Engager (BiTE)
  • BCMA
  • Phase 3

Accepting patients

Sonrotoclax (BGB-11417)

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
  • BCL-2 Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

CaMMouflage

A Phase 1, Multicenter, Open-Label Study of CB-011, a CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma (CaMMouflage Trial)
  • CAR T Cell (Allogeneic)
  • BCMA
  • Phase 1
  • Has results

Accepting patients

TRIgnite-1

A Phase 1, First-in-Human, Multicenter, Open-Label, Dose Escalation and Dose-Expansion Study of Single-Agent ISB 2001 in Subjects With Relapsed/Refractory Multiple Myeloma
  • T Cell
  • Trispecific Antibody
  • CD38
  • BCMA
  • Phase 1
  • Has results

Accepting patients

FASTER

Frontline T-cell Engager vs Autologous Stem Cell Transplant and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma (FASTER)
  • Bispecific Antibody
  • Autologous Stem Cell Transplant
  • BCMA
  • Phase 2

Accepting patients

MASTER-2

Sequential Therapy in Multiple Myeloma Guided by MRD Assessments
  • Proteasome Inhibitor
  • Randomization
  • Minimal Residual Disease (MRD)
  • Phase 2

Not yet accepting

RECLAIM

BCMA Bispecific Antibody Therapy for Post-BCMA CAR T-Cell Therapy Relapse (RECLAIM)
  • Bispecific T Cell Engager (BiTE)
  • Bispecific Antibody
  • BCMA
  • Post-CAR T
  • Phase 2

Not yet accepting

FT836 CAR T-cell Therapy

Phase I Study of FT836 CAR T-cell Therapy in Combination With Daratumumab in Patients With Relapsed and/or Refractory Multiple Myeloma
  • CAR T Cell (Allogeneic)
  • T Cell (Allogeneic)
  • MICA
  • MICB
  • Phase 1
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